Biomaterials Lab., Kansai University

関西大学 生体材料学研究室


  • Thongthai P, Kitagawa H*, Kitagawa R, Hirose N, Noree S, Iwasaki Y, Imazato S. Development of novel surface coating composed of MDPB and MPC with dual functionality of antibacterial activity and protein repellency, J. Biomed. Mater. Res. B 2020;in press.

  • Iwasaki Y*, Bunuasunthon S, Hoven V*. Protein patterning with antifouling polymer gel platforms generated using visible light irradiation, Chem. Commun. 2020;in press.

  • Otaka A, Yamaguchi T, Saisho R, Hiraga T, Iwasaki Y*. Bone-targeting phospholipid polymers to solubilize the lipophilic anticancer drug, J. Biomed. Mater. Res. A 2020;in press.

  • Nakano H, Noguchi Y, Kakinoki S, Yamanaka M, Osaka I, Iwasaki Y*. Highly durable lubricity of photo-cross-linked zwitterionic polymer brushes supported by poly (ether ether ketone) substrate, ACS Appli. Bio Mater. 2020;3:1071−1078.

  • Noree S, Thobthai P, Kitagawa H, Imazato S, Iwasaki Y*. Reduction of scidic erosion and oral bacterial adhesion through the immobilization of zwitterionic polyphosphoesters on mineral substrates, Chem. Lett. 2019;48:1529-1532.

  • Hiranphinyophat S, Asaumi Y, Fujii S, Iwasaki Y*. Surface grafting polyphosphoesters on cellulose nanocrystals to improve the emulsification efficacy, Langmuir, 2019;35:11443-11451.

  • Sae-ung P, Wijitamornloet A, Iwasaki Y, Thanyasrisung P, Hoven V*. Clickable zwitterionic copolymer as a universal biofilm-resistant coating, Macromol. Mater. Eng. 2019;304:1900286.

  • Kunomura S, Iwasaki Y*. Immobilization of polyphosphoesters on poly(ether ether ketone) (PEEK) for facilitating mineral coating, J. Biomater. Sci., Polym. Edn. 2019;30:861-876.

  • Otaka A*, Iwasaki Y*. Endocytosis of poly(ethylene sodium phosphate) by macrophages and the effect of polymer length on cellular uptake, J. Ind. Eng. Chem. 2019;75:115-122.

  • Noree S, Iwasaki Y*. Thermally assisted generation of protein–poly(ethylene sodium phosphate) conjugates with high mineral affinity, ACS Omega 2019;4:3398-3404.
    DOI: 10.1021/acsomega.8b03585

  • Iwasaki S, Kawasaki H, Iwasaki Y*. Label-free specific detection and collection of C-reactive protein using zwitterionic phosphorylcholine-polymer-protected magnetic nanoparticles, Langmuir 2019;35:1749-1755.

  • Kambe Y, Tokushige T, Mahara A, Iwasaki Y, Yamaoka T*. Cardiac differentiation of induced pluripotent stem cells on elastin-like protein-based hydrogels presenting a single cell adhesion sequence, Polym. J. 2019;51:97-105.

  • Sugimoto S, Iwasaki Y*. Surface modification of macrophages with nucleic acid aptamers for enhancing the immune response against tumor cells, Bioconjugate Chem. 2018;29:4160-4167.

  • Iwasaki Y*, Yokota A, Otaka A, Inoue N, Yamaguchi A, Yoshitomi T, Yoshimoto K, Neo M. Bone-targeting poly(ethylene sodium phosphate), Biomater. Sci. 2018;6:91-95.

  • Tanaka M, Kawai S, Iwasaki Y*. Well-defined protein immobilization on photo-responsive phosphorylcholine polymer surfaces, J. Biomater. Sci. Polym. Edn., 2017;28:2021-2033.
    DOI: 10.1080/09205063.2017.1366251

  • Hirano Y, Iwasaki Y*. Bone-specific poly(ethylene sodium phosphate)-bearing biodegradable nanoparticles, Colloids Surf., B, 2017;153:104-110.
    DOI: 10.1016/j.colsurfb.2017.02.015

  • Sangsuwan A, Kawasaki H, Matsumura Y, Iwasaki Y*. Antimicrobial silver nanoclusters bearing biocompatible phosphorylcholine based zwitterionic protects, Bioconjugate Chem. 2016;27:2527-2533.
    DOI: 10.1021/acs.bioconjchem.6b00455

  • Iwasaki Y*,Takemoto K, Tanaka S, Taniguchi I. Low-temperature processable block copolymers that preserve the function of blended proteins, Biomacromolecules 2016;17:2466-2471.

  • Iwasaki Y*, Kondo J, Kuzuya A, Moriyama R. Crosslinked duplex DNA nanogels that target specified proteins, Sci. Tech. Adv. Mater. 2016;17:285-292.

  • Ohata T, Ishihara K, Iwasaki Y, Sangsuwan A, Fujii S, Sakurai K, Ohara Y, Yusa S*. Water-soluble complex formation of fullerene with biocompatible polymer, Polym. J. 2016;48:999-1005.

  • Tanaka M, Iwasaki Y*. Photo-assisted generation of phospholipid polymer substrates for regiospecific protein conjugation and control of cell adhesion, Acta Biomater. 2016;40:54-61.

  • Wiarachai O, Vilaivan T, Iwasaki Y, Hoven V*. Clickable and anti-fouling platform of poly[(propargyl methacrylate)-ran-(2-methacryloyloxyethyl phosphorylcholine)] for biosensing applications, Langmuir 2016;32:1184–1194.

  • Sangsuwan A, Kawasaki H, Iwasaki Y*. Thiolated-2-methacryloyloxyethyl phosphorylcholine protected silver nanoparticles as novel photo-induced cell-killing agents, Colloids Surf., B 2016;140:128-134.

  • Yamazoe H*, Ichikawa T, Hagihara Y, Iwasaki Y. Generation of a patterned co-culture system composed of adherent cells and immobilized nonadherent cells, Acta Biomater. 2016;31:231-240. DOI:10.1016/j.actbio.2015.12.016

  • Yoshimoto J, Sangsuwan A, Osaka I, Yamashita K, Iwasaki Y, Inada M, Arakawa R, Kawasaki H*. Optical Properties of 2-Methacryloyloxyethyl Phosphorylcholine-Protected Au4 Nanoclusters and Their Fluorescence Sensing of C-Reactive Protein, J. Phys. Chem. C 2015;119:14319–14325.

  • Sugimoto S, Moriyama R, Mori T, Iwasaki Y*. Surface engineering of macrophages with nucleic acid aptamers for circulating tumor cell capture, Chem. Commun. 2015;51:17428-17430.
    DOI: 10.1039/C5CC06211J

  • Kootala S, Tokunaga M, Hilborn J, Iwasaki Y*. Anti-resorptive functions of poly(ethylene sodium phosphate) on human osteoclasts, Macromol. Biosci. 2015;15:1634-1640.
    DOI: 10.1002/mabi.201500166

  • Moriyama R*, Iwasaki Y, Miyoshi D. Stabilization of DNA structures with poly(ethylene sodium phosphate). J. Phys. Chem. B 2015;119:11969–11977.
    DOI: 10.1021/acs.jpcb.5b03787

  • Iwasaki Y*, Takahata Y, Fujii S. Self-setting particle-stabilized emulsion for hard-tissue engineering. Colloids Surf., B 2015;126:394-400.
    DOI: 10.1016/j.colsurfb.2014.12.003

  • Iwasaki Y*, Matsunaga A, Fujii S. Preparation of biointeractive glycoprotein-conjugated hydrogels through metabolic oligosacchalide engineering. Biocomjugate Chem. 2014;25:1626-1631.
    DOI: 10.1021/bc5003295

  • Kawasaki Y, Iwasaki Y*. Surface modification of poly(ether ether ketone) with methacryloyl-functionalized phospholipid polymers via self-initiation graft polymerization. J. Biomater. Sci., Polym. Edn. 2014;25:895-906.

  • Iwasaki Y*, Kimura T, Orisaka M, Kawasaki H, Goda T*, Yusa S. Label-free detection of C-reactive protein using highly dispersible gold nanoparticles synthesized by reducible biomimetic block copolymers. Chem. Commun. 2014;50:5656-5658.
    DOI: 10.1039/C4CC01855A

  • Tamura A, Tokunaga M, Iwasaki Y, Yui N*. Spontaneous assembly into pseudopolyrotaxane between cyclodextrins and biodegradable polyphosphoester ionomers. Macromol. Chem. Phys. 2014;215:648-653.
    DOI: 10.1002/macp.201300774

  • Goda T*, Tabata M, Sanjoh M, Uchimura M, Iwasaki Y*, Miyahara Y*. Thiolated 2-Methacryloyloxyethyl phosphorylcholine for antifouling biosensor platform. Chem. Commun. 2013;49:8683-8685.
    DOI: 10.1039/C3CC44357D

  • Iwasaki Y*, Sakiyama M, Fujii S, Yusa S. Surface modification of mammalian cells with stimuli-responsive polymers. Chem. Commun. 2013;49:7824-7826.

  • Iwasaki Y*, Katayama K, Yoshida M, Yamamoto M, Tabata Y. Comparative physicochemical properties and cytotoxicity of polyphosphoester ionomers with bisphosphonates. J. Biomater. Sci., Polym. Edn. 2013;24:882-895.

  • Ikeuchi R, Iwasaki Y*. High mineral affinity of polyphosphoester ionomer-phospholipid vesicles. J. Biomed. Mater. Res. A 2013;101A:318-325.
    DOI: 10.1002/jbm.a.34321

  • Iwasaki Y*, Matsumoto A, Yusa S. Optimized molecular structure of photoreactive biocompatible block copolymers for surface modification of metal substrate. ACS Appl. Mater. Interfaces 2012;4:3254-3260.
    DOI: 10.1021/am3006065

  • Ikeuchi R, Iwasaki Y*. Synthesis of amphiphilic polyphosphoester ionomers for surface modification of small unilamellar phospholipid vesicles. Trans. Mater. Res. Soc. Jpn. 2012;37:365-368.
    DOI: 10.14723/tmrsj.37.365

  • Akkahat P, Kiatkamjornwong S, Yusa S, Hoven VP*, Iwasaki Y*. Development of a novel anti-fouling platform for biosensing probe immobilization from methacryloyloxyethyl phosphorylcholine-containing copolymer brushes. Langmuir 2012;28:5872-5881.
    DOI: 10.1021/la204229t

  • Iwasaki Y*, Matsuno H. Metabolic delivery of methacryloyl groups on living cells and cell surface modification via thiol-ene "click" reaction. Macromol. Biosci. 2011:11;1478-1483.
    DOI: 10.1002/mabi.201100242

  • Iwasaki Y*, Ota T. Efficient biotinylation of methacryloyl-functionalized nonadherent cells for formation of cell microarrays. Chem. Commun. 2011;10329-10331.
    DOI: 10.1039/C1CC12948A

  • Nakai K, Morigaki K, Iwasaki Y*, Molecular recognition on fluidic lipid bilayer microarray corralled by well-defined polymer brushes. Soft Matter 2010;6:5937-5943.
    DOI: 10.1039/C0SM00086H

  • Iwasaki Y*, Shibata Y, Watanabe A, Inada M, Kawasaki H, Uchino T. One-pot preparation of water-soluble blue luminescent silica flakes via microwave heating. Chem. Lett. 2010;39:370-371.

  • Iwasaki Y*, Yamaguchi E. Synthesis of well-defined thermoresponsive polyphosphoester macroinitiators using organocatalysts. Macromolecules 2010;43:2664-2666.
    DOI: 10.1021/ma100242s

  • Iwasaki Y*, Kawakita T, Yusa S. Thermoresponsive polyphosphoesters bearing enzyme-cleavable side chains. Chem. Lett. 2009; 38, 1054-1055.

  • Iwasaki Y*, Omichi Y. Iwata R. Site-specific dense immobilization of antibody fragments on polymer brushes supported by silicone nanofilaments. Langmuir 2008;24:8427-8430.
    DOI: 10.1021/la801327a

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